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Filtered Search Results
Medchemexpress LLC HY-107139 10mg Medchemexpress, JNJ-10229570 CAS:524923-88-4 Purity:>98%
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Medchemexpress, HY-107139 10mg JNJ-10229570 CAS:524923-88-4 JNJ-10229570 is an antagonist of melanocortin receptor 1 (MC1R) and melanocortin receptor 5 (MC5R), which inhibits sebaceous gland differentiation and the production of sebum-specific lipids. JNJ-10229570 inhibits the binding of 125I-NDP-α-MSH to cells expressing human MC1R and MC5R, with IC50 values of 270 nM and 200 nM, respectively. Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
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Medchemexpress LLC N-[(3R,4S)-3-hydroxy-2,2-dimethyl-6-(4,4,4-trifluorobutoxy)chroman-4-yl]-N-methylmethanesulfonamide | 223749-46-0 | MFCD12756323 | 100.0% | 411.44 | C17H24F3NO5S | 10 MG
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HMR 1556 is a chromanol-derived small molecule that selectively inhibits the I_Ks (slow delayed rectifier potassium) current. It exhibits potent activity in cardiac myocytes with reported IC50 values in the low nanomolar range and is supplied as a high-purity research reagent in solid and solution formats.
- Potent and selective Iks channel blocker.
- Reported IC50s of 10.5 nM (canine) and 34 nM (guinea pig).
- High reported purity (99.95%).
- Available as solid and as DMSO solution formats.
- Multiple package sizes to suit experimental scale.
- For research use only; not for human or clinical use.
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Medchemexpress LLC Hxr9 hydrochloride | 99.5% | 2754.67 | 5 MG
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HXR9 hydrochloride is a cell-permeable peptide and a competitive antagonist of HOX/PBX interaction. It antagonizes the interaction between HOX and PBX, a transcription factor that binds to HOX proteins in paralogue groups 1 to 8. It selectively decreases cell proliferation and promotes apoptosis in cells with high HOXA/PBX3 genes expression, such as MLL-rearranged leukemic cells.
- Cell-permeable peptide
- Competitive antagonist of HOX/PBX interaction
- Decreases cell proliferation in cells with high HOXA/PBX3 genes expression
- Promotes apoptosis in cells with high HOXA/PBX3 genes expression
- Blocks the interaction between PBX and HOX
- Exhibits antiproliferative activity
- Blocks tumor growth in vivo
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Medchemexpress LLC 2-(Hydroxy(4-phenoxyphenyl)methylene)malononitrile | 330792-68-2 | C16H10N2O2 | 100 MG
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This product is a laboratory chemical intended for research use only, suitable for the manufacture of substances. It should be handled by experienced personnel in appropriately equipped facilities and has not been fully validated for medical applications.
- Identified uses: laboratory chemicals, manufacture of substances.
- Appearance: solid.
- Melting/freezing point: 160-161.2°C.
- Recommended storage for powder: -20°C for 3 years, 4°C for 2 years.
- Recommended storage in solvent: -80°C for 6 months, -20°C for 1 month.
- Shipping at room temperature if less than 2 weeks.
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Medchemexpress LLC HY-120056 10mg Medchemexpress, YKL-06-061 CAS:2172617-15-9 Purity:>98%
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Medchemexpress, HY-120056 10mg YKL-06-061 CAS:2172617-15-9 YKL-06-061 is a potent, selective, second-generation salt-inducible kinase (SIK) inhibitor with IC50 values of 6.56 nM/1.77 nM/20.5 nM for SIK1/2/3, respectively. Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
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eMolecules 1211537-08-4 | 4,5-Difluoropyridin-2-amine | MFCD18259315 | 100mg
Ambeed | 2-(Methyl(phenyl)amino)-2-oxoacetic acid | 100mg | 601097542 | A567282 | 13120-33-7 | MFCD09864583 | 179.175 | C9H9NO3
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eMolecules 845272-21-1 | Medchem Express | Varlitinib | 5mg | 446258822 | HY-10530 | MFCD20275099 | 466.94 | C22H19ClN6O2S
Medchem Express | Varlitinib | 5mg | 446258822 | HY-10530 | 845272-21-1 | MFCD20275099 | 466.940 | C22H19ClN6O2S
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Medchemexpress LLC HY-10864 100mg Medchemexpress, URB-597 KDS-4103 CAS:546141-08-6 Purity:98%
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Medchemexpress,HY-10864 100mg URB-597 KDS-4103 CAS:546141-08-6 Formula:C20H22N2O3 Purity:98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
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Medchemexpress LLC HY-103050 5mg Medchemexpress, ML-030 CAS:1013750-77-0 Purity:>98%
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Medchemexpress, HY-103050 5mg ML-030 CAS:1013750-77-0 ML-030 is a potent PDE4 inhibitor, with IC50 of 6.7 nM, 12.9 nM, 48.2 nM, 37.2 nM, 452 nM and 49.2 nM for PDE4A, PDE4A1, PDE4B1, PDE4B2, PDE4C1,and PDE4D2, respectively. Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
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eMolecules 1260665-75-5 | Ambeed | 5-Chloro-3-methylpyrazine-2-carbonitrile | 100mg | 714086174 | A448763 | MFCD18250189 | 153.57 | C6H4ClN3
Ambeed | 2-Bromo-6-chloro-4-fluorobenzaldehyde | 250mg | 525202370 | A386761 | 1433990-64-7 | MFCD28733865 | 237.450 | C7H3BrClFO
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Medchemexpress LLC HY-112607 10mg Medchemexpress, Tubulin inhibitor 1 CAS:2237054-53-2 Purity:>98%
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Medchemexpress, HY-112607 10mg Tubulin inhibitor 1 CAS:2237054-53-2 Tubulin inhibitor 1 is a tubulin inhibitor, inhibits tubulin polymerization. Tubulin inhibitor 1 shows potent anti-tumor activity, casues cellular mitotic arrest in the G2/M phase, and induces cellular apoptosis. Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
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Medchemexpress LLC HY-10223 5mg Medchemexpress, CUDC-101 CAS:1012054-59-9 Purity:>98%
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Medchemexpress, HY-10223 5mg CUDC-101 CAS:1012054-59-9 CUDC-101 is a potent inhibitor of HDAC , EGFR , and HER2 with IC 50 s of 4.4, 2.4, and 15.7 nM, respectively. Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
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Medchemexpress LLC MBX-2982 | 1037792-44-1 | MFCD12918809 | C22H24N8OS | 100 MG
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MBX-2982 is a selective, orally-available G protein-coupled receptor 119 (GPR119) agonist.
- Increased cAMP accumulation in pre-treated cells
- Demonstrated a significant shift in concentration responses
- Elevated plasma GLP-1 levels in mice, independent of glucose load
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Medchemexpress LLC Repaglinide-d5 | 1217709-85-7 | C27H31D5N2O4 | 1 MG
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Repaglinide-d5 is deuterium labeled Repaglinide, an insulin secretagogue for the treatment of type-2 diabetes mellitus. It reduces postprandial glucose levels by enhancing the early phase of insulin secretion and increasing the total amount of insulin secreted.
- Can be used as a tracer
- Can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS
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Medchemexpress LLC Arn 077 (URB913) | 1373625-34-3 | 98.8% | 10MG
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Arn 077 (URB913) | 1373625-34-3 | 98.8% | 10MG
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